Alendronate sodium trihydrate, 97%

Description

CAS: 121268-17-5 | C4H18NNaO10P2 | 325.122 g/mol

Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

Solubility
Soluble in water at 10mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 121268-17-5
• Molecular Formula: C4H18NNaO10P2
• Molecular Weight (g/mol): 325.122
• MDL Number: MFCD01748233
• InChI Key: DCSBSVSZJRSITC-UHFFFAOYSA-M
• Synonym: alendronate sodium hydrate, alendronate sodium trihydrate, alendronate sodium, alendronate monosodium trihydrate, alendros, adronat, fosamax, sodium alendronate hydrate, elandor, fosalan
• PubChem CID: 23681107
• ChEBI: CHEBI:2566
• IUPAC Name: sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate
• SMILES: C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]

• Color: White
• Quantity: 1 g
• Merck Index: 14,229
• Solubility Information: Soluble in water at 10mg/ml
• Formula Weight: 325.12 (271.08 Anhydrous)
• Percent Purity: 97%
• Physical Form: Solid
• Chemical Name or Material: Alendronate sodium trihydrate

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
RTECSNumber	SZ6523500
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only