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Medchemexpress LLC Alexidine dihydrochloride | 1715-30-6 | ≥98% | 581.71 | 1 ML
Supplier: Medchemexpress LLC HY10854710MM/1ML
Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells, leading to mitochondrial apoptosis. It also exhibits broad-spectrum antifungal and antibiofilm activity against various fungal pathogens, including fluconazole-resistant strains and mature biofilms.
- Targets mitochondrial tyrosine phosphatase (PTPMT1).
- Induces mitochondrial apoptosis.
- Shows broad-spectrum antifungal activity against diverse fungal pathogens.
- Effective against fluconazole-resistant Candida isolates.
- Inhibits filamentation and proliferation of fungi.
- Decimates mature biofilms of Candida, Cryptococcus, and Aspergillus species at low concentrations.
- Inhibits lateral yeast formation and biofilm dispersal in C. albicans.
- Reduces fungal biofilm growth and viability by 67% in C. albicans murine models.
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