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Apexbio Technology LLC Alfuzosin HCl 81403-68-1 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A51735.1
Alfuzosin HCl (CAS 81403-68-1) is a functionally uroselective antagonist of sub 1 /sub adrenoceptors that exhibits no subtype selectivity among sub 1 /sub receptor isoforms By blocking sub 1 /sub adrenoceptors it inhibits smooth muscle contraction in the lower urinary tract In pharmacological assays Alfuzosin HCl suppresses phenylephrine-induced increases in intraurethral pressure by approximately 81% demonstrating significant activity with minimal cardiovascular effects This compound is utilized in research investigating sub 1 /sub adrenoceptor-mediated pathways relevant to urinary tract function and related pharmacology
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