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Cayman Chemical aLInolenIc AcIdodIum salt 50mg
SDP

Supplier:  Cayman Chemical 2191050 MG

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A synthetic progestin and PR agonist (EC50s 3 4-10 5 nM in transactivation assays) selective for PR over ERa and ERB as well as glucocorticoid and mineralocorticoid receptors (EC50s 3000 nM for all) as well as SHBG and CBG (IC50s 900-950 and 7970 nM respectively in radioligand binding assays) inhibits dihydrotestosterone-induced transactivation of the androgen receptor (EC50s 420 6-775 nM) reduces lesion formation in a rat model of endometriosis at 0 1 0 3 and 1 mg/kg per day for 21 days orally reduces 17b-estradiol benzoate-dependent tumor growth in an MCF-7 ovariectomized mouse xenograft model at 0 1 and 1 mg/kg per day for 28 days

Catalog No. 50-296-4164


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