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Apexbio Technology LLC Aliskiren Hemifumarate 173334-58-2 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B22155.1
Aliskiren Hemifumarate (CAS 173334-58-2) is a small molecule classified as a direct renin inhibitor By binding to renin it blocks the initial step in the renin-angiotensin-aldosterone system (RAAS) thereby reducing the conversion of angiotensinogen to angiotensin I and lowering downstream angiotensin II levels This mechanism results in decreased vasoconstriction and aldosterone-mediated sodium retention Aliskiren Hemifumarate is primarily studied in the context of essential hypertension and serves as a tool compound for exploring renin-dependent regulatory pathways and therapeutic strategies targeting blood pressure homeostasis
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