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Cayman Chemical Alkyn-Cyclo RGDyKtrIfluor 10mg
Supplier: Cayman Chemical 4172210 MG
A degrader of NSD2 induces degradation of NSD2 (DC50 350 nM) selective for NSD2 over NSD1 and NSD3 at 20 UM induces NSD2 degradation and reduces H3K35me2 in MM.1S cells at 10 UM reduces the proliferation of MM.1S cells expressing NSD2 containing an activating NSD2E1099K mutation but not MDA-MB-231 U2OS or HEK293 cells expressing wild-type NSD2 at 20 UM decreases attachment of MM.1S cells in a migration assay at 20 UM
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