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Medchemexpress LLC Allopurinol sodium | 17795-21-0 | 99.90% | 100 MG
Supplier: Medchemexpress LLC HYB0219A100MG
Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor (IC₅₀ value of 0.2-50 μM) used in research for hyperuricemia and gout. It decreases the expression of HIF-1α and HIF-2α protein, and also demonstrates anti-depressant, anti-nociception, and anti-leishmanial effects.
- Potent and orally active xanthine oxidase inhibitor
- Research applications include hyperuricemia and gout
- Decreases expression of HIF-1α and HIF-2α protein
- Exhibits anti-depressant and anti-nociception activity
- Shows anti-leishmanial effect
- Reduces angiogenesis traits in HUVEC cells
- Reduces elevated IL-6 levels and phosphorylation of JAK2 and STAT3
- Normalizes mitochondrial damage in cardiomyocytes
- Upregulates HPRT, XOR, PNP, Nrf2, SOD-1, and CAT genes
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