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Medchemexpress LLC Almonertinib hydrochloride (HS-10296 hydrochloride) | 2134096-03-8 | 98.92% | 562.11 | 25 MG
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Catalog No. 5000439418
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Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor. It exhibits high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows strong inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively) and is less effective against the wild type (3.39 nM). It is used in the research of non-small cell lung cancer.

  • Orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor.
  • High selectivity for EGFR-sensitizing and T790M resistance mutations.
  • Strong inhibitory activity against T790M, T790M/L858R, and T790M/Del19.
  • Less effective against wild type.
  • Used in the research of non-small cell lung cancer.

Catalog No. 50-004-39418 Supplier Medchemexpress LLC Supplier No. 25MGHY112823B
May include imposed supplier surcharges.
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Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor. It exhibits high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows strong inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively) and is less effective against the wild type (3.39 nM). It is used in the research of non-small cell lung cancer.

  • Orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor.
  • High selectivity for EGFR-sensitizing and T790M resistance mutations.
  • Strong inhibitory activity against T790M, T790M/L858R, and T790M/Del19.
  • Less effective against wild type.
  • Used in the research of non-small cell lung cancer.

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