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Medchemexpress LLC Almorexant hydrochlo 10mM 1mL | 913358-93-7 | 10MM 1ML

Supplier: Medchemexpress LLC HY10805A10MM 1ML
Almorexant (ACT 078573) hydrochloride is an orally active potent and competitive dual orexin receptor antagonist with Kd values of 1 3 nM (OX1) and 0 17 nM (OX2) respectively Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides Almorexant hydrochloride totally blocked the intracellular Ca2 signal pathway Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis[1 [2 [3 [4
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