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Cayman Chemical AlmotrIptnmalate 50mg
SDP

Supplier:  Cayman Chemical 2564650 MG

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A dual inhibitor of c-Met and VEGFR2 inhibits autophosphorylation of c-Met and phosphorylation of VEGFR2 (IC50s 14 and 16 nM respectively) inhibits proliferation in a variety of cancer cell lines inhibits proliferation of HUVECs stimulated with HGF and VEGF but not bFGF (IC50s 17 84 and 1000 nM) reduces tumor volume dose-dependently in nude mouse xenograft models using MKN45 Hs746T SNU-5 or EBC-1 cells increases survival of nude mice implanted with MKN45 cancer cells

Catalog No. 50-293-6012


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