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Cayman Chemical Alntolacton 50mg
Supplier: Cayman Chemical 2976250 MG
A sesquiterpene lactone with diverse biological activities; inhibits LPS-induced increases in nitric oxide, IL-6, and TNF-α production in RAW 246.7 cells by 76.09, 81.54, and 71.23%, respectively, at 10 μM; decreases cell viability, GSH levels, and the mitochondrial membrane potential, induces apoptosis, and increases ROS generation in HepG2 cells at 40 μM; inhibits phosphorylation and nuclear translocation of STAT3 in MDA-MB-231 cells; reduces tumor growth in an MDA-MB-231 mouse xenograft model at 2.5 mg/kg
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