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Cayman Chemical AlolIthocholIc AcId-d4 10mg
SDP

Supplier:  Cayman Chemical 4115610 MG

Encompass_Preferred

An RRM2 inhibitor (IC50 8.2 UM) decreases HBV DNA replication in infected HepG2 2.2.15 cells (EC50 45.8 UM) and reduces HBV DNA levels in the supernatant and lysates of infected HepG2 2.2.15 cells (EC50s 11.1 and 16.5 UM respectively) inhibits the replication of 3TC-resistant HBV in infected HepG2 cells (EC50 19.8 UM) reduces HepG2 Huh7 and HCCLM3 cell proliferation in a concentration-dependent manner and decreases the proliferation of a variety of esophageal squamous cell carcinoma cells (IC50s 144.8-182.3 UM) reduces HBV DNA levels in serum and liver tissues in a transgenic mouse model of HBV infection at 400 mg/kg per day reduces tumor growth in combination with radiation in radiation-sensitive and -resistant KYSE-150 esophageal squamous cell carcinoma mouse xenograft models at 200 mg/kg per day

Catalog No. 50-294-4621


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