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Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 10 MM * 1 ML
Supplier: Medchemexpress LLC HY70050C10MM/1ML
Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist, utilized for irritable bowel syndrome (IBS) research. It blocks 5-HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons (IC50 ~55 nM), attenuates visceral nociceptive effects, and demonstrates anti-inflammatory effects.
- Potent and highly selective serotonin 5-HT3 receptor antagonist.
- Used for research of irritable bowel syndrome.
- Blocks 5HT3-mediated depolarisation of neurons.
- Attenuates visceral nociceptive effects.
- Demonstrates anti-inflammatory effects.
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