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Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 100 MG
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Supplier:  Medchemexpress LLC HY70050C100MG

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Alosetron Hydrochloride is a potent and highly selective serotonin 5-HT3 receptor antagonist used in research for irritable bowel syndrome (IBS). It blocks the fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM. It also attenuates visceral nociceptive effects of rectal distension in dogs and demonstrates anti-inflammatory properties.

  • Potent and highly selective serotonin 5-HT3 receptor antagonist
  • Applicable for research in irritable bowel syndrome (IBS)
  • Blocks fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM
  • Attenuates visceral nociceptive effects of rectal distension in dogs
  • Demonstrates anti-inflammatory effects

Catalog No. 50-004-34584


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