Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.63% | C17H19ClN4O | 50 MG
Supplier: Medchemexpress LLC HY70050C50MG
Alosetron Hydrochloride is a potent and highly selective antagonist of the serotonin 5-HT3 receptor. It is researched for its application in irritable bowel syndrome (IBS). The compound effectively blocks the rapid 5HT3-mediated depolarization in guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM. It also demonstrates an ability to lessen the visceral nociceptive effects of rectal distension in conscious or anesthetized dogs, and exhibits anti-inflammatory properties.
- Highly selective antagonist of the serotonin 5-HT3 receptor.
- Under investigation for irritable bowel syndrome.
- Blocks 5HT3-mediated depolarization.
- Attenuates visceral nociceptive effects.
- Exhibits anti-inflammatory effects.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?