Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | C19H23ClF3N5O2S | 500 MG
Supplier: Medchemexpress LLC HY15244A500MG
Alpelisib hydrochloride (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor with efficacy in targeting PIK3CA-mutated cancer. It exhibits antineoplastic activity.
- Potent, orally active, and selective PI3Kα inhibitor
- Inhibits PIK3CA somatic mutations (H1047R, E545K)
- Inhibits Akt phosphorylation in PI3Kα transformed cells
- Induces G0/G1 phase cell cycle arrest in osteosarcoma cell lines
- Significantly reduces tumor volumes in animal models
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?