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AdipoGen alpha-Actinin-4 pAb IG-701
SDP

Supplier:  AdipoGen AG25T0107C050

Encompass_Preferred

Polyclonal Antibody. Recognizes human, mouse, rat, pig and Chinese hamster actinin-4. Does not cross-react with actinin-1, -2 or -3. Source Rabbit. Applications IHC, IP, WB. Liquid. In PBS containing 1mg/ml BSA and 0.01% sodium azide. alpha-Actinin 4 is an actin-bundling protein of ~100kDa that is associated with cell motility, endocytosis and cancer invasion. The alpha-actinin family comprises two non-muscle isoforms alpha-actinin-1 and -4 and two skeletal muscle isoforms alpha-actinin-2 and -3, with alpha-actinin-2 being also expressed in cardiac muscle. While alpha-actinin-4 is almost ubiquitously expressed, particularly high concentrations are found in glomeruli. On the subcellular level it is associated with actin stress fibers, but in certain cells it also localizes to the nucleus.

Catalog No. 50-256-3166


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