Thermo Scientific Chemicals alpha-Apo-oxytetracycline, 'can be used as secondary standard'

Description

Alpha-Apo-oxytetracycline, CAS # 18695-01-7, is considered a metabolite formed from oxytetracycline, a member of the tetracycline family, and displays antibiotic activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information
• Alpha-Apo-oxytetracycline is a degradation product of oxytetracycline. When this degradation occurs, two isomers are generated, β- and α -apo-oxytetracycline

Applications
• Alpha-Apo-oxytetracycline compound presents antibiotic activity
• It promotes the inhibition of the growth of aerobic sludge bacteria, Pseudomonas, Agrobacterium, Moraxella, Bacillus, as well as tetracycline-resistant strains of E. coli

Specifications

Chemical Identifiers

• CAS: 18695-01-7
• Molecular Formula: C₂₂H₂₂N₂O₈
• Molecular Weight (g/mol): 442.39
• MDL Number: MFCD00062827
• InChI Key: DRKMHDAKULCOKQ-UHFFFAOYSA-N
• Synonym: beta-apo-oxytetracycline, alpha-apo-oxytetracycline, alpha-apooxytetracycline, alpha-apoterramycin, beta-apo oxytetracycline, 2z-2-amino hydroxy methylidene-5-4,5-dihydroxy-9-methyl-3-oxo-1h-benzo f 2 benzofuran-1-yl-4-dimethylamino-6-hydroxycyclohexane-1,3-dione, 4-1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho 2,3-c furan-1-yl-3-dimethylamino-2,5-dihydroxy-6-oxo-1-cyclohexene-1-carboxamide, 4-4,5-dihydroxy-9-methyl-3-oxo-1,3-dihydronaphtho 2,3-c furan-1-yl-3-dimethylamino-2,5-dihydroxy-6-oxocyclohex-1-ene-1-carboxamide, 4-4,5-dihydroxy-9-methyl-3-oxohydrobenzo f isobenzofuranyl-3-dimethylamino-2,5-dihydroxy-6-oxocyclohex-1-enecarboxamide, 4-4,5-dihydroxy-9-methyl-3-oxo-1h-naphtho 2,3-c furan-1-yl-3-dimethylamino-2,5-dihydroxy-6-oxocyclohex-1-ene-1-carboxamide
• PubChem CID: 54710410
• IUPAC Name: 4-(4,5-dihydroxy-9-methyl-3-oxo-1H-benzo[f][2]benzofuran-1-yl)-3-(dimethylamino)-2,5-dihydroxy-6-oxocyclohexene-1-carboxamide
• SMILES: CC1=C2C(OC(=O)C2=C(C3=C1C=CC=C3O)O)C4C(C(=C(C(=O)C4O)C(=O)N)O)N(C)C

• Melting Point: 200.0°C
• Color: Khaki
• Infrared Spectrum: Authentic
• Assay Percent Range: 80% min. (as is,calculated)
• Packaging: Glass bottle
• Quantity: 100 mg
• Merck Index: 10, 6846
• Specific Rotation: − 64.00
• Solubility Information: Solubility in water: insoluble. Other solubilities: soluble in alkaline solution and ammonia
• Formula Weight: 442.39
• Percent Purity: ≥97.0% (on anhydrous substance), ≥80 wt% (as is, calculated)(HPLC)
• Physical Form: Crystalline Powder
• Chemical Name or Material: α-Apo-oxytetracycline, (can be used as secondary standard)

Safety and Handling

Hazard Category	GHS Signal Word: Warning
Hazard Statement	GHS H Statement: Causes serious eye irritation. Suspected of damaging the unborn child.
Precautionary Statement	GHS P Statement: Use personal protective equipment as required. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

SDS

RUO – Research Use Only