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Medchemexpress LLC Alpha-Ionone | 127-41-3 | MFCD00001565 | 192.30 | 1 ML
SDP

Supplier:  Medchemexpress LLC HYN884710MM/1ML

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Alpha-Ionone (α-Ionone) is a chemical compound with the molecular formula C13H20O and a molecular weight of 192.30. It functions as an activator of the olfactory receptor OR10A6 and is known to induce apoptosis by stimulating the LATS-YAP-TAZ signaling axis within the Hippo pathway. This compound demonstrates inhibitory effects on tumor formation both in vitro and in vivo. It targets various pathways including Hippo (MST), YAP, Olfactory Receptor, and Apoptosis.

  • Activates olfactory receptor OR10A6
  • Induces apoptosis by activating LATS-YAP-TAZ signaling
  • Inhibits tumor formation in vitro and in vivo
  • Increases cAMP in A431 cells with an EC50 of 152.4 μM
  • Inhibits proliferation and migration of A431 and HaCaT cells
  • Modulates key proteins involved in apoptosis, including caspase-3, BAX, and BCL-2
  • Suppresses growth of A431 cell xenograft in animal models

Catalog No. 50-004-25267


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