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  8. AM 281, Tocris Bioscience™

AM 281, Tocris Bioscience™

Catalog No. 111510
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective CB1 inverse agonist

Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM).

Chemical Identifiers

CAS 202463-68-1
Molecular Formula C21H19Cl2IN4O2
Molecular Weight (g/mol) 557.21
MDL Number MFCD01861180
InChI Key AJFFBPZYXRNAIC-UHFFFAOYSA-N
Synonym unii-sbp4a4dyh2, sbp4a4dyh2, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-4-morpholinyl-1h-pyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-morpholin-4-ylpyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-morpholino-1h-pyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-morpholin-4-yl pyrazole-3-carboxamide, tocris-1115, d0ud9h, gtpl741, 1h-pyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-4-morpholinyl
PubChem CID 4302962
IUPAC Name 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(morpholin-4-yl)-1H-pyrazole-3-carboxamide
SMILES CC1=C(N(N=C1C(=O)NN1CCOCC1)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(I)C=C1

Specifications

Quantity 10 mg
Formula Weight 557.22
Percent Purity >99%
Chemical Name or Material AM 281

Safety and Handling

Recommended Storage Desiccate at +4°C
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