Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organic acids and derivatives
  6. Carboxylic acids and derivatives
  7. Carboxylic acid hydrazides
  8. AM 281, Tocris Bioscience™

AM 281, Tocris Bioscience™

Catalog No. 111550
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
11-155-0 50 mg
11-151-0 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 11-155-0 Supplier R&D Systems Supplier No. 1115/50
This item is not returnable. View return policy

Description

Potent and selective CB1 inverse agonist

Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR141716A (Ki = 14 nM).

Chemical Identifiers

CAS 202463-68-1
Molecular Formula C21H19Cl2IN4O2
Molecular Weight (g/mol) 557.21
MDL Number MFCD01861180
InChI Key AJFFBPZYXRNAIC-UHFFFAOYSA-N
Synonym unii-sbp4a4dyh2, sbp4a4dyh2, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-4-morpholinyl-1h-pyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-morpholin-4-ylpyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-morpholino-1h-pyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-morpholin-4-yl pyrazole-3-carboxamide, tocris-1115, d0ud9h, gtpl741, 1h-pyrazole-3-carboxamide, 1-2,4-dichlorophenyl-5-4-iodophenyl-4-methyl-n-4-morpholinyl
PubChem CID 4302962
IUPAC Name 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(morpholin-4-yl)-1H-pyrazole-3-carboxamide
SMILES CC1=C(N(N=C1C(=O)NN1CCOCC1)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(I)C=C1

Specifications

Quantity 50 mg
Formula Weight 557.22
Percent Purity >99%
Chemical Name or Material AM 281

Safety and Handling

Recommended Storage Desiccate at +4°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.