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Medchemexpress LLC AM-5308 | 2410796-89-1 | 99.2% | C26H35N5O5S | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14489450MG

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AM-5308 is an inhibitor for KIF18A that inhibits KIF18A-mediated microtubule ATPase activity. It activates mitotic checkpoints, regulates cell division processes, and exhibits antitumor activity.

  • Inhibits KIF18A-mediated microtubule ATPase activity
  • Activates mitotic checkpoints
  • Regulates cell division processes, including chromosome segregation and spindle assembly
  • Exhibits antitumor activity
  • Shows cytotoxicity in human bone marrow cells in vitro
  • Arrests cell cycle of MDA-MB-157 and human bone marrow cells in mitosis phase in vitro
  • Demonstrates antitumor activity in mouse OVCAR-3 xenograft models in vivo

Catalog No. 50-003-55066


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