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Medchemexpress LLC Amantadine | 768-94-5 | 99.9% | 100 G
Supplier: Medchemexpress LLC HYB0402100G
Amantadine is an orally active and potent antiviral agent effective against influenza A viruses and coronaviruses. It inhibits various ion channels, including NMDA and M2, and shows anti-orthopoxvirus and anticancer activities. This compound is suitable for research applications related to Parkinson's disease, postoperative cognitive dysfunction, and COVID-19.
- Inhibits influenza A viruses and coronavirus ion channels
- Demonstrates anti-orthopoxvirus and anticancer activity
- Suitable for research on Parkinson's disease and COVID-19
- Inhibits SARS-CoV-2 replication in Vero E6 cells
- Markedly inhibits proliferation of HepG2 and SMMC 7721 cells
- Arrests cell cycle at G0/G1 phase and induces apoptosis
- Reduces cyclin D1, cyclin E, and CDK2 levels
- Increases Bax protein and mRNA levels while decreasing Bcl-2
- Inhibits surgery-induced neuroinflammation and learning impairment in rats
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