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Medchemexpress LLC AMG 487 | 473719-41-4 | C32H28F3N5O4 | 100 MG
SDP

Catalog No. 5000372534
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AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3). It inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.

  • Targets CXCR3
  • Involved in GPCR/G Protein and immunology/inflammation pathways
  • Inhibits CXCR3-mediated cell migration
  • Inhibits calcium mobilization
  • Leads to fewer lung metastases
  • Reduces tumor volume

Catalog No. 50-003-72534 Supplier Medchemexpress LLC Supplier No. HY15319100MG
May include imposed supplier surcharges.
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AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3). It inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.

  • Targets CXCR3
  • Involved in GPCR/G Protein and immunology/inflammation pathways
  • Inhibits CXCR3-mediated cell migration
  • Inhibits calcium mobilization
  • Leads to fewer lung metastases
  • Reduces tumor volume

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