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Medchemexpress LLC HY-108642B 1mg Medchemexpress, AMG-548 (dihydrochloride) CAS: Purity:>98%
Supplier: Medchemexpress LLC HY108642B1MG
Medchemexpress, HY-108642B 1mg AMG-548 (diHCl) CAS: AMG-548 dihydrochloride, an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ. AMG-548 dihydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM). AMG-548 dihydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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