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Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1291310MG

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AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. It has shown a statistically significant reduction of PCP induced behavior in rats.

  • Potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A)
  • IC50 of 0.1 nM for phosphodiesterase 10A
  • Statistically significant reduction of PCP induced behavior in rats
  • Minimum effective dose of 0.3 mg/kg for efficacy in PCP-LMA model
  • Exhibits a superior oral bioavailability of 72% in dogs

Catalog No. 50-003-39172


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