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Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 100 MG
SDP

Supplier:  Medchemexpress LLC HY12913100MG

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AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. It is intended for research use only. In vivo, it significantly reduced PCP-induced behavior in rats over a 2-hour period with a minimum effective dose of 0.3 mg/kg, and in dogs, it exhibits a superior oral bioavailability of 72%.

  • Potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A)
  • Has an IC50 of 0.1 nM
  • Significantly reduces PCP-induced behavior in rats
  • Exhibits superior oral bioavailability in dogs (72%)
  • For research use only

Catalog No. 50-003-39367


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