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Medchemexpress LLC AMG 837 calcium hydrate | 1259389-38-2 | 99.0% | 455.45 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY13967B10MM/1ML

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AMG 837 calcium hydrate is a potent, orally bioavailable, and partial agonist of GPR40/FFA1. It inhibits specific binding at the human FFA1 receptor with a pIC50 of 8.13. This compound can enhance insulin secretion and lower glucose levels in rodents.

  • Stimulates insulin secretion in a glucose-dependent manner.
  • Stimulates Ca2+ flux in human, mouse, and rat receptors.
  • Reduces glucose levels and increases insulin levels in vivo.
  • Improves glucose tolerance and enhances insulin secretion.
  • Displays excellent oral bioavailability.
  • Click chemistry reagent containing an alkyne group.

Catalog No. 50-003-50422


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