Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000385046

Medchemexpress LLC AMI-1 | 20324-87-2 | 98.0% | 548.45 | 25 MG
SDP

Catalog No. 5000385046
Encompass_Preferred

AMI-1 is a potent, cell-permeable, and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM for human PRMT1 and 3.0 μM for yeast-Hmt1p. It inhibits PRMTs by blocking peptide-substrate binding.

  • Potent, cell-permeable, and reversible inhibitor
  • Inhibits in vitro methylation reactions performed by PRMT1, -3, -4, -6, and Hmt1p
  • Inhibits both type I and type II PRMTs
  • Specifically inhibits arginine methyltransferase activity
  • Does not compete for the AdoMet binding site
  • Inhibits methylation of GFP-Npl3 and cellular proteins

Catalog No. 50-003-85046 Supplier Medchemexpress LLC Supplier No. 25MGHY18962
May include imposed supplier surcharges.
Add to Cart
Add to Cart

AMI-1 is a potent, cell-permeable, and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM for human PRMT1 and 3.0 μM for yeast-Hmt1p. It inhibits PRMTs by blocking peptide-substrate binding.

  • Potent, cell-permeable, and reversible inhibitor
  • Inhibits in vitro methylation reactions performed by PRMT1, -3, -4, -6, and Hmt1p
  • Inhibits both type I and type II PRMTs
  • Specifically inhibits arginine methyltransferase activity
  • Does not compete for the AdoMet binding site
  • Inhibits methylation of GFP-Npl3 and cellular proteins

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.