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Medchemexpress LLC Amifostine thiol dihydrochloride | 14653-77-1 | MFCD00460339 | >98.0% | 207.16 g·mol⁻¹ | C5H16Cl2N2S | 1 ML
Supplier: Medchemexpress LLC HY10364010MM 1ML
Amifostine thiol dihydrochloride (WR-1065 dihydrochloride) is the active thiol metabolite of amifostine used as a research reagent for radioprotection and cytoprotection. It is reported to protect normal tissues from the toxic effects of certain chemotherapeutic and radiotherapeutic agents and to activate p53 via a JNK-dependent signaling pathway, making it useful in studies of apoptosis, DNA damage response, and MDM2-p53 signaling.
- Cytoprotective and radioprotective research reagent suitable for cellular assays.
- Reported to activate p53 through a JNK-dependent signaling pathway.
- Provided as a ready-to-use 10 mM solution (1 mL) for experimental convenience.
- Also available in solid formats for formulation or analytical applications.
- Useful for apoptosis, DNA damage response, and MDM2-p53 pathway studies.
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