AG Scientific Inc Amikacin, 1 G

Supplier:  AG Scientific Inc A27411GM

Amikacin, a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. It works by stopping the growth of bacteria. Similar to the other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites leading to the production of non-functional or toxic peptides.The amino group of amikacin at position 1 is acylated by 4-amino-2-hydroxybutyrate. The presence of the aminohydroxybutyryl group in general prevents the enzymatic modification of amikacin at multiple positions. This antibiotic undergoes acetylation by different types of AAC(6′), as well as by a few other aminoglycoside-modifying enzymes such as AAC(2′), APH(2""), and ANT(2"").CAS Number: 37517-28-5Molecular Weight: 585.6 DaChemical Formula: C22H43N5O13Solubility: WaterStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.

Catalog No. 50-223-6885