Amikacin disulfate

Description

An aminoglycoside antibiotic derived from Kanamycin A | CAS: 39831-55-5 | C22H47N5O21S2 | 781.75 g/mol

Amikacin disulfate is used as an aminoglycoside antibiotic derived from Kanamycin A, used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter. It is commonly used in the treatment of drug-resistant mycobacteria. It is used to study organism-directed delivery of antibiotics as well as drug resistance.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amikacin disulfate is used as an aminoglycoside antibiotic derived from Kanamycin A, used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter. It is commonly used in the treatment of drug-resistant mycobacteria. It is used to study organism-directed delivery of antibiotics as well as drug resistance.

Solubility
Soluble in water at 50mg/ml with warming

Notes
Potency: 674-786 micrograms per mg

Specifications

Chemical Identifiers

• CAS: 39831-55-5
• Molecular Formula: C22H47N5O21S2
• Molecular Weight (g/mol): 781.75
• MDL Number: MFCD00167475,MFCD00167475
• InChI Key: FXKSEJFHKVNEFI-GCZBSULCSA-N
• PubChem CID: 134129615
• IUPAC Name: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide; bis(sulfuric acid)
• SMILES: OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O

• Type: Amikacin Disulfate
• Physical Form: Powder
• Melting Point: 220°C to 230°C
• Color: White
• Quantity: 25 g
• Beilstein: 6172633
• Merck Index: 14,405
• Solubility Information: Soluble in water at 50mg/ml with warming
• Formula Weight: 781.77
• Chemical Name or Material: Amikacin disulfate

Safety and Handling

EINECSNumber	254-648-6
RTECSNumber	WK1961200
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only