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Amikacin, MP Biomedicals™

Catalog No. MP21503422 Shop All MP Biomedicals, Inc Products
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MP21503422 250 mg
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Catalog No. MP21503422 Supplier MP Biomedicals, Inc Supplier No. 02150342.2
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Description

Used to treat different types of bacterial infections. Amikacin, MP Biomedicals is an aminoglycoside antibiotic most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Ente

Amikacin works by binding to the bacterial 30S ribosomal subunit, inducing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. It interferes with the translocation of tRNA from the A-site to the P-site. Amikacin must be given by the intravenous or intramuscular route; it is not absorbed orally.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 37517-28-5
Molecular Formula C22H43N5O13
Molecular Weight (g/mol) 585.608
InChI Key LKCWBDHBTVXHDL-RMDFUYIESA-N
Synonym 1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A, O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine, Lukadin
PubChem CID 37768
ChEBI CHEBI:2637
IUPAC Name (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
SMILES C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N

Specifications

Physical Form Powder
pH 9.5 to 11.5 (1% aq. soln.)
Potency ca. 900μg/mg
Quantity 250 mg
Optical Rotation 100.5°
Boiling Point 981.8°C (760mmHg)
Solubility Information Sparingly soluble in water.
Formula Weight 585.6

Safety and Handling

Recommended Storage Store at 4°C, desssicated.
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