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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | MFCD03703482 | 99.8% | 500 MG
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Supplier:  Medchemexpress LLC HYB0285A500MG

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Amiloride hydrochloride is a research chemical that acts as an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). It also functions as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is intended for research use only.

  • Inhibits epithelial sodium channel (ENaC).
  • Inhibits urokinase-type plasminogen activator receptor (uTPA).
  • Blocks polycystin-2 (PC2; TRPP2) channel.
  • Selective inhibitor of ENaC with an IC50 ranging from 0.1 to 0.5 μM.
  • Reverses and prevents increases in collagen deposition in DOCA-salt hypertensive rats.
  • Delays proteinuria and improves brain and kidney scores in SHRSP rats.
  • Antagonizes aldosterone actions in cardiovascular and renal tissues.

Catalog No. 50-004-07023


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