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Sigma Aldrich Amino-Peg6-T-Butyl Ester

Catalog No. 9026591G Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-265-91G 1 g
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Catalog No. 90-265-91G Supplier Sigma Aldrich Supplier No. 9026591G
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC™ molecules) for targeted protein degradation.PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Specifications

CAS 849830-54-2
Melting Point 202°C to 206°C
Molecular Formula C35H54N2OSi2Pt
Refractive Index n/D 1.4562
Linear Formula C35H54N2OSi2Pt
Quantity 1 g
Synonym tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate; H2N-PEG6-CH2CH2COOtBu
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