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Medchemexpress LLC Aminoguanidine hydrochloride | 1937-19-5 | ≥98.0% | 500 MG
Supplier: Medchemexpress LLC HYB1041500MG
Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. It exhibits a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin and possesses antioxidant properties. It can be utilized in diabetic nephropathy research.
- Inhibitor of diamine oxidase and nitric oxide synthase.
- Dose-dependent inhibitory effect on apoptosis induced by Doxorubicin.
- Possesses antioxidant properties.
- Can be used in diabetic nephropathy research.
- Exhibits anti-inflammatory activity against mouse RAW264.7 cells by inhibiting LPS-induced NO production.
- Can reduce DOX-induced DNA damage and apoptosis in A549 cells.
- Can induce ERK activation and promote cell proliferation in AR42J cells.
- Protects mice from CCl4-induced hepatotoxicity.
- Protective against cyclophosphamide (CP)-induced oxidative stress and kidney damage in rats.
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