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Medchemexpress LLC Amisulpride | 71675-85-9 | MFCD00866691 | 99.8% | C17H27N3O4S | 200 MG
Supplier: Medchemexpress LLC HY14545200MG
Amisulpride is a racemic (50:50) mixture of R-Amisulpride and S-Amisulpride. It acts as a dopamine D2/D3 receptor antagonist with Ki values of 2.8 nM for human dopamine D2 and 3.2 nM for human dopamine D3 receptors. Amisulpride also functions as a 5-HT7 receptor antagonist with a Ki of 44 nM, making it suitable for use in psychiatric research.
- Racemic mixture
- Dopamine D2/D3 receptor antagonist
- 5-HT7 receptor antagonist
- Suitable for psychiatric research
- D3 receptor Ki: 3.2 nM
- Human D2 receptor Ki: 2.8 nM
- 5-HT7 receptor Ki: 44 nM
- Inhibits quinpirole-elicited [3H]thymidine incorporation
- Increases dopamine release from rat striatum slices
- Increases dopamine synthesis in rat striatum and limbic system
- Increases extracellular dopamine levels
- Decreases striatal ACh levels
- Increases duration of swimming behavior
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