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Medchemexpress LLC Amisulpride (hydrochloride) | 81342-13-4 | 99.8% | C17H28ClN3O4S | 25 MG
Supplier: Medchemexpress LLC 25MGHY14545A
Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist, with Ki values of 2.8 nM for human dopamine D2 and 3.2 nM for human dopamine D3. It is an atypical antagonist intended for research use only.
- Inhibits quinpirole-elicited [3H]thymidine incorporation with an IC50 value of 22±3 nM.
- Slightly increases [3H]dopamine release from rat striatum slices.
- Reduces dopamine levels in the striatum or limbic system at high doses.
- Increases dopamine synthesis in rat striatum and limbic system.
- Increases extracellular dopamine levels.
- Decreases striatal ACh levels.
- Increases the duration of swimming behavior in acute studies.
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