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Apexbio Technology LLC Amitriptyline HCl 549-18-8 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC B22315.1

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Amitriptyline HCl (CAS 549-18-8) is a tricyclic compound that modulates multiple neurotransmitter systems It acts as an inhibitor at serotonin and norepinephrine receptors demonstrating potent activity with IC50 values of 3 45 nM and 13 3 nM respectively Amitriptyline also exhibits notable affinity for 5-HT4 (IC50 7 31 nM) 5-HT2 (IC50 235 nM) and sigma-1 receptors (IC50 287 nM) indicating a broad spectrum of receptor interactions This pharmacological profile supports its application in neuropharmacological research including studies of synaptic transmission antidepressant mechanisms and receptor signaling pathways

Catalog No. 50-000-89877


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