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Medchemexpress LLC Amitriptyline hydrochloride | 549-18-8 | MFCD00012537 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HYB0527A10MM/1ML
Amitriptyline hydrochloride is an orally active tricyclic antidepressant primarily blocking SERT and NET, which elevates 5-hydroxytryptamine and norepinephrine in the synaptic cleft. It also functions as an α2A and TrkA/TrkB receptor agonist, providing analgesic and neurotrophic benefits by inhibiting cell apoptosis. This compound can reduce inflammation, angiogenesis, and fibrosis. It binds to DAT and various other receptors, while also capable of blocking sodium and hERG potassium channels.
- Primarily blocks SERT and NET
- Increases 5-hydroxytryptamine and norepinephrine in synaptic cleft
- Acts as α2A and TrkA/TrkB receptor agonist
- Provides analgesic and neurotrophic activities
- Inhibits cell apoptosis
- Reduces inflammation, angiogenesis, and fibrosis
- Binds to DAT and multiple cholinergic, H1, and adrenergic receptors
- Can block sodium and hERG potassium channels
- For research use only
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