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Medchemexpress LLC Amodiaquine dihydrochloride dihydrate | 6398-98-7 | 99.9% | 1 ML
SDP

Catalog No. 5000411973
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Amodiaquine dihydrochloride dihydrate is a 4-aminoquinoline class antimalarial agent. It functions as a potent and orally active inhibitor of histamine N-methyltransferase and acts as a Nurr1 agonist. This compound also exhibits anti-inflammatory and neuroprotective effects, suppressing pro-inflammatory cytokines.

  • Antimalarial agent, effective against malaria.
  • Potent and orally active histamine N-methyltransferase inhibitor.
  • Nurr1 agonist, specifically binds to the Nurr1-LBD with an EC50 of ~20 μM.
  • Anti-inflammatory effects.
  • Solution form: available as a 10 mM * 1 mL solution in DMSO with a purity of 99.92%.
  • Neuroprotective effects: inhibits neurotoxin-induced cell death in primary dopamine cells and has effects in rat PC12 cells.
  • Suppresses LPS-induced expression of pro-inflammatory cytokines.

Catalog No. 50-004-11973 Supplier Medchemexpress LLC Supplier No. HYB132210MM/1ML
May include imposed supplier surcharges.
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Amodiaquine dihydrochloride dihydrate is a 4-aminoquinoline class antimalarial agent. It functions as a potent and orally active inhibitor of histamine N-methyltransferase and acts as a Nurr1 agonist. This compound also exhibits anti-inflammatory and neuroprotective effects, suppressing pro-inflammatory cytokines.

  • Antimalarial agent, effective against malaria.
  • Potent and orally active histamine N-methyltransferase inhibitor.
  • Nurr1 agonist, specifically binds to the Nurr1-LBD with an EC50 of ~20 μM.
  • Anti-inflammatory effects.
  • Solution form: available as a 10 mM * 1 mL solution in DMSO with a purity of 99.92%.
  • Neuroprotective effects: inhibits neurotoxin-induced cell death in primary dopamine cells and has effects in rat PC12 cells.
  • Suppresses LPS-induced expression of pro-inflammatory cytokines.

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