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Genscript Corporation Antibody Protein Proteins Proteins 10 UG 1/EA
Supplier: Genscript Corporation Z0310310
Amphiregulin is a member of the EGF family of cytokines which comprises at least ten proteins including EGF TGF-Alpha HB-EGF Epiregulin Tomoregulin Neuregulins and the various heregulins. Through the EGF/TGF-Alpha receptor it stimulates growth of keratinocytes epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein Amphiregulins extracellular domain is proteolytically processed to release the mature protein.
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