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Medchemexpress LLC AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) | ≥98.0% | Approximately 38 kDa (PRKAB1) & 40 kDa (PRKAG1) & 95 kDa (PRKAA1), based on SDS-PAGE under reducing conditions. | 5 UG
Supplier: Medchemexpress LLC HYP761415UG
AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is a recombinant human-derived protein expressed by Sf9 insect cells with N-His and N-GST labeled tags. It functions as the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a critical regulator of cellular energy metabolism. Activated by low ATP levels, AMPK enhances energy production while inhibiting biosynthetic processes and cell growth, thereby maintaining cellular energy homeostasis.
- Specific activity determined to be 53 nmol/min/mg
- Expressed in Sf9 insect cells
- N-His and N-GST labeled tags
- Purity greater than 98.0% by SDS-PAGE
- Endotoxin level less than 1 EU/μg
- Stable at -80°C for 1 year from receipt
- Formulated as a 0.22 μm filtered solution of 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 7.5
- Approximate molecular weights: 38 kDa (PRKAB1), 40 kDa (PRKAG1), 95 kDa (PRKAA1)
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