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Medchemexpress LLC Amxi-5001 hydrochloride | 98.05% | C25H21ClFN5O3 | 50 MG
Supplier: Medchemexpress LLC HY145734A50MG
AMXI-5001 hydrochloride is a potent, orally active compound that acts as a dual inhibitor of parp1/2 and microtubule polymerization. It demonstrates selective antitumor cytotoxicity across various human cancer cells, with significantly lower IC50s compared to existing clinical PARP1/2 inhibitors. AMXI-5001 hydrochloride has been shown to induce complete regression of established tumors, including large ones.
- Potent, orally active, dual parp1/2 and microtubule polymerization inhibitor.
- Exhibits selective antitumor cytotoxicity in a wide range of human cancer cells.
- Shows much lower IC50s than current clinical PARP1/2 inhibitors.
- Capable of inducing complete regression of established tumors, including exceedingly large tumors.
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