Medchemexpress LLC Anabasine ((S)-Anabasine) | 494-52-0 | MFCD00006370 | 99.0% | 100 MG

Supplier:  Medchemexpress LLC HYB1532100MG

Anabasine ((S)-Anabasine) is an alkaloid found as a minor component in tobacco. It functions as a botanical pesticide nicotine and acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). It induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs, with an EC50 of 0.7 μM. Studies show it significantly reverses impairment at 0.2 mg/kg and 2 mg/kg doses.

• Functions as a botanical pesticide nicotine
• Acts as a full agonist of nicotinic acetylcholine receptors (nAChRs)
• Induces depolarization of TE671 cells with an EC50 of 0.7 μM
• Significantly reverses impairment at 0.2 mg/kg and 2 mg/kg doses
• Does not significantly affect response latency when administered alone
• Exacerbates dizocilpine-induced impairment at 0.06 mg/kg dose
• Does not independently affect choice accuracy

Catalog No. 50-004-11185