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Apexbio Technology LLC Anagrelide HCl 58579-51-4 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC A43525.1
Anagrelide hydrochloride (CAS 58579-51-4) is a selective thrombocytopenic agent approved for the treatment of essential thrombocythemia Its primary mechanism involves inhibiting the maturation of megakaryocytes thereby reducing platelet production without significantly affecting leukocytes or erythrocytes Orally administered anagrelide demonstrates platelet-lowering effects at doses as low as 0 5 mg In preclinical studies anagrelide exhibits positive inotropic and vasodilatory properties with additional implications for use in other myeloproliferative disorders such as polycythemia vera and chronic myeloid leukemia Its application extends to research on thrombopoiesis and related hematological pathologies
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