Angelicin (CAS No 523-50-2) is a naturally occurring furanocoumarin primarily isolated from plants like Angelica archangelica It is studied in the biomedical research category particularly for its photobiological properties Its mechanism of action involves the intercalation into DNA forming covalent bonds upon ultraviolet light exposure which disrupts DNA replication and transcription Angelicin exhibits activity in the nanomolar to low micromolar range It is commonly used in in vitro studies for cell models to investigate its effects on cell cycle regulation and apoptosis Animal studies explore its therapeutic potential for conditions such as psoriasis and vitiligo Additionally Angelicin serves as an agent in drug screening particularly for photochemotherapy research Experimental concentrations typically depend on the specific research design