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Medchemexpress LLC Angiopeptin TFA | 2478421-60-0 | 99.01% | 1326.39 | 25 MG
Supplier: Medchemexpress LLC 25MGHYP2090A
Angiopeptin TFA is a cyclic octapeptide analogue of somatostatin. It acts as a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. It is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA also inhibits adenylate cyclase or stimulates extracellular acidification, making it valuable for research in coronary atherosclerosis.
- Acts as a partial agonist on the release of tritium on CHO hsst2 cells (in vitro).
- Significantly inhibits neointimal formation (in vivo).
- Significantly inhibits coronary artery myointimal proliferation in cardiac allografts (in vivo).
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