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Sigma Aldrich Fine Chemicals Biosciences Angiotensin Converting Enz
Supplier: Sigma Aldrich Fine Chemicals Biosciences SAE006450UG
The gene for angiotensin converting enzyme-2 (ACE-2) is mapped to human chromosome Xp22.2. This protein is the first known human homologue of ACE. ACE2 has been identified from 5AE sequencing of a human heart failure ventricle cDNA library. It contains a signal peptide one metalloprotease active site and a transmembrane domain. ACE-2 is a secreted and an integral membrane protein. It is expressed predominantly on the endothelium.
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