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AdipoGen ANGPTL4 FLD h pAb

Supplier: AdipoGen AG25A0065C100
Polyclonal Antibody. Recognizes the fibrinogen-like domain of human ANGPTL4. Detects a band of ~38kDa by Western blot. Weakly cross-reacts with human ANGPTL3 fibrinogen-like domain, ANGPTL5 fibrinogen-like domain, ANGPTL6 fibrinogen-like domain and ANGPTL6. Does not cross-react with ANGPTL4 coiled-coil domain or other ANGPTL family proteins. Source Rabbit. Applications ELISA, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. ANGPTL4 mainly expressed in endothelial cells hypoxia-induced. Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain FLD. Both domains have distinct biological functions.
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